Individual participant data meta-analyses compared with meta-analyses based on aggregate data
نویسندگان
چکیده
منابع مشابه
Individual participant data meta-analyses compared with meta-analyses based on aggregate data
BACKGROUND Meta-analyses based on individual participant data (IPD-MAs) allow more powerful and uniformly consistent analyses as well as better characterisation of subgroups and outcomes, compared to those which are based on aggregate data (AD-MAs) extracted from published trial reports. However, IPD-MAs are a larger undertaking requiring greater resources than AD-MAs. Researchers have compared...
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Jayne Tierney and colleagues offer guidance on how to spot a well-designed and well-conducted individual participant data meta-analysis.
متن کاملIndividual Participant Data (IPD) Meta-analyses of Diagnostic and Prognostic Modeling Studies: Guidance on Their Use
1 Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands, 2 The Dutch Cochrane Centre, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands, 3 Research Institute for Primary Care and Health Sciences, Keele University, Staffordshire, The United Kingdom, 4 Radboud Institute for Heal...
متن کاملHow individual participant data meta-analyses have influenced trial design, conduct, and analysis
OBJECTIVES To demonstrate how individual participant data (IPD) meta-analyses have impacted directly on the design and conduct of trials and highlight other advantages IPD might offer. STUDY DESIGN AND SETTING Potential examples of the impact of IPD meta-analyses on trials were identified at an international workshop, attended by individuals with experience in the conduct of IPD meta-analyses...
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ژورنال
عنوان ژورنال: Trials
سال: 2011
ISSN: 1745-6215
DOI: 10.1186/1745-6215-12-s1-a57